Percentage of patients with a baseline creatinine increase of more than 1.5 times within 7 postoperative days or the baseline creatinine level increases by ≥ 0.3 mg/dL within 48 hours postoperatively.

Acute kidney injury is a serious complication following non-cardiac surgery and is associated with an increased risk of in-hospital mortality. ^1,2 The development of AKI is known to increase patient care demands, accounting for 20% of intensive care unit (ICU) admissions, and significantly increasing hospital cost, length of stay, and mortality. AKI is also associated with development or progression of chronic kidney disease.³ Definitions and classification schema for AKI vary across current literature; most commonly, these include the Risk/Injury/Failure/Loss/End-stage (RIFLE), Acute Kidney Injury Network (AKIN), and Kidney Disease-Improving Global Outcomes (KDIGO) criteria.⁴ This measure most closely aligns with KDIGO AKI criteria, with exceptions of: a) not considering postoperative urine output or renal replacement therapy components of the definition (data are commonly unavailable); b) not considering cases in which a ≥ 0.3 mg/dL increase in serum creatinine level occurred greater than 48 hours but less than 7 days postoperative.

Up to 48 hours after Anesthesia End

All patients requiring anesthesia.

• ASA 5 & 6 including Organ Procurement (CPT:01990)
• Cases where a baseline creatinine is not available within 60 days preoperatively
• Cases where a creatinine lab is not available within 7 postoperative days.
• Patients with pre-existing renal (stage 4 or 5) failure based upon BSA-Indexed EGFR < 30 mL/min/1.73m^2 determined by Preop EGFR (most recent) or MPOG Complication - Acute Kidney Injury value code -2.
• Procedures:
  • ECT
  • Labor Epidurals (determined by the Obstetric Anesthesia Type value codes: 3 & 6 including obstetric non-operative procedures - CPT: 01958)
  • Pain Procedures – CPT 01991, 01992, 01996
  • Renal & Liver Transplants – CPT 00868, 00796
  • Procedures affecting the kidney, bladder, or ureter:
  • • Anesthesia CPT: 00862, 00864, 00870, 00872, 00873, 00865, 00908, 00910, 00912, 00914, 00916, 00918, 00860, 00942 
    • Surgical CPT Codes *See other measure build details.
• Surgery duration less than 45 minutes

1. The creatinine level does not go above 1.5x the baseline creatinine within 7 days post-op
2. The creatinine level does not increase by ≥ 0.3 mg/dL obtained within 48 hours after anesthesia end.

For patients with more than one case in a 7-day period, postoperative creatinine values only apply to a single case. For example, if a creatinine value is available between the end of the first case and start of the second case, that value will only apply to the first case. If additional values result within the 7-day time period after the second case, those values will not be attributed to the first case. 

Only valid creatinine values (≥0.2 mg/dL and ≤25.00 mg/dL) are considered. Method for calculating eGFR is dependent on age and gender data. If gender is not available, phenotype assumes female. Height is required for calculating eGFR for pediatric patients. See Preop EGFR (most recent) for calculation.

The AKI stage definitions can be viewed in detail here: MPOG Complication - Acute Kidney Injury 

AKI- Risk of Progression to CKD Phenotype is available per case in the 'Measure Case Report Tool'. 

The following Surgical CPT Codes are excluded from this measure:

*This measure will include only valid MPOG cases as defined by the Is Valid Case phenotype.

Coming soon!

1. The provider(s) signed in during the case when the BP 01 or BP 03 measure failed (it is possible to have more than one provider).
2. If there is no failure for the BP 01 or BP 03 measure, then the responsible provider(s) is the provider signed in the longest.

1. Abelha FJ, Botelho M, Fernandes V, Barros H. Determinants of postoperative acute kidney injury. Critical care (London, England). 2009;13(3):R79
2. Bellomo R, Ronco C, Kellum JA, Mehta RL, Palevsky P. Acute renal failure - definition, outcome measures, animal models, fluid therapy and information technology needs: the Second International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI) Group. Critical care (London, England). Aug 2004;8(4):R204-212.
3. Lameire, Norbert H., Adeera Levin, John A. Kellum, Michael Cheung, Michel Jadoul, Wolfgang C. Winkelmayer, Paul E. Stevens, and Conference Participants. 2021. “Harmonizing Acute and Chronic Kidney Disease Definition and Classification: Report of a Kidney Disease: Improving Global Outcomes (KDIGO) Consensus Conference.” Kidney International 100 (3): 516–26.
4. Levey, Andrew S. 2022. “Defining AKD: The Spectrum of AKI, AKD, and CKD.” Nephron 146 (3): 302–5.
5. James, Matthew T., Neesh Pannu, Brenda R. Hemmelgarn, Peter C. Austin, Zhi Tan, Eric McArthur, Braden J. Manns, et al. 2017. “Derivation and External Validation of Prediction Models for Advanced Chronic Kidney Disease Following Acute Kidney Injury.” JAMA: The Journal of the American Medical Association 318 (18): 1787–97.